The Eleventh Annual Wiley Prize in Biomedical Sciences is awarded to Dr. James Spudich, Dr. Michael Sheetz, and Dr. Ronald Vale for explaining how cargo is moved by molecular motors along two different systems of tracks within cells.

Many basic cellular functions depend on the directed movement of macromolecules, membranes or chromosomes from one place to another within the cell. The transport of this intracellular cargo is achieved by molecular motor proteins, such as myosin and kinesin, which provide force and movement through the conversion chemical energy (ATP) into mechanical energy. Molecular motor proteins move along scaffolds made of specific protein polymers (kinesin along microtubules and myosin along actin filaments) carrying their cargo to its proper place in the cell.

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The Wiley Prize in Biomedical Sciences is intended to recognize breakthrough research in pure or applied life science research that is distinguished by its excellence, originality and impact on our understanding of biological systems and processes.This international award is presented annually and consists of a $35,000 prize and a luncheon in honor of the recipient. The award is presented at a ceremony at The Rockefeller University, where the recipient delivers an honorary lecture as part of The Rockefeller University Lecture Series.

Submit your nomination by July 31, 2012.